PBC itch management

Itch, or pruritus, is a common symptom for up to 80% of people living with primary biliary cholangitis (PBC).

woman itching her arm (actor portrayal)

Continued discussion about the importance of PBC itch has led to the availability of some treatment options that help address it. It’s important to take steps to manage your itch where you can, and to discuss your experiences with your doctor.

FACTS ABOUT ITCH

Up to 80% of people living with PBC experience itch

People with PBC itch say it feels like:

  • Deep itch inside the body or under the skin
  • Bugs crawling under the skin
  • A burning sensation

I was experiencing symptoms like itching on the bottoms of my feet, my hands.

Jackeline Candelario, living with PBC

a woman is sharing her experience and symptoms

Person featured was compensated by Gilead.

Some experience it all over, while others feel it in specific areas such as:

  • Hands and feet
  • Scalp
  • Back
  • Legs

30% of those with itch say it is so bad, it impacts their daily lives

Itch can cause:

  • Damage and scarring of the skin from scratching
  • Difficulty sleeping, leading to fatigue
  • Missing work, school, or social activities due to embarrassment or fear of judgment

People with PBC itch are about 2x more likely to also experience fatigue

If itch keeps you up at night, it makes sense that fatigue will follow. However, researchers have discovered there may be a scientific link between PBC itch and chronic fatigue. This means treatment strategies that help with itch could possibly help fatigue as well.

Compared to alkaline phosphatase (ALP), itch may not be top of mind for your doctor

That’s why it’s important to speak up about:

  • When itch affects you most (for example, day or night)
  • Any associated triggers or patterns you identify
  • How frequently it happens
  • How long episodes last

My fatigue and my itchiness were telling me something was wrong with my body.

Suzanne Anderson, living with PBC

a woman describes her symptoms, fatigue, and itching

Person featured was compensated by Gilead.

CAUSES AND TREATMENT OPTIONS

Itch is worth talking about. Ask your doctor about treatments that may help reduce itch.

MANAGEMENT STRATEGIES

Do’s and don’t’s for PBC itch

While they might not take away all the itch, here are a few methods you can try that may help. You may need to ask your doctor for their recommendation or more information.

Shower, bathing, and personal care

  • Use mild, nonalkaline soaps and oils
  • Take baths or showers with lukewarm water
  • Limit showers or baths to 20 minutes
  • Do not bathe with hot water
  • Avoid rubbing your skin after showering/bathing

Clothing

  • Wear soft clothing made from natural materials like cotton
  • Avoid tight clothes
  • Avoid wool sweaters
  • Do not use scented detergents

Ingredients to look for

  • Use mild moisturizers that contain synthetic urea to help hold water and soften skin
  • Try creams, salves, or lotions with cooling or anesthetic qualities with ingredients like menthol
  • Avoid irritating herbs like chamomile or tea tree oil

Lifestyle

  • Consider using ultraviolet (UV) phototherapy
  • Reduce stress as much as possible
  • Avoid consuming large amounts of hot or spicy food, hot drinks, or alcohol

Share strategies with others living with PBC.

The information provided is not meant to override your treatment plan or advice from your healthcare team.

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